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. 2009 Dec 22;115(9):1843–1849. doi: 10.1182/blood-2009-07-231068

Table 3.

Multivariate analyses of relapse

Variable n RR (95% Confidence interval) P
All patients*
    0-MM 56 0.7 (0.4-1.3) .211
    1-MM 352 Reference
    2-MM 588 0.9 (0.6-1.2) .364
    3-MM 65 1.2 (0.7-2.2) .458
Patients in relapse
    0-MM 7 1.0 (0.2-4.4) .977
    1-MM 77 Reference
    2-MM 142 0.9 (0.5-1.5) .693
    3-MM 28 1.4 (0.6-3.1) .394
Patients in remission
    0-MM 40 0.7 (0.3-1.5) .359
    1-MM 228 Reference
    2-MM 371 0.9 (0.6-1.4) .662
    3-MM 32 1.5 (0.6-3.8) .411
Patients who engrafted
    0-MM 47 0.7 (0.4-1.4) .350
    1-MM 254 Reference
    2-MM 418 1.0 (0.7-1.4) .804
    3-MM 45 1.7 (0.9-3.4) .108

MM indicates mismatch; and RR, relative risk.

*

Other predictive variables, such as advanced disease, diagnosis of JCML, and younger age (< 10 years), were associated with an increased risk of relapse. TNC, transplant center experience, year of transplant, and patient ethnicity were not predictive of relapse.

The subanalyses of those transplanted in relapse or remission excludes those with unknown disease status at time of transplantation and MDS.