Table 1.
Demographic and Clinical Characteristics of Subjects at Baseline Examination According to Quartiles of Total Cholesterol (mg/dl).
| Overall | Q1 (TC<164) |
Q2 (164<TC<189) |
Q3 (189<TC<215) |
Q4 (TC>215) |
|
|---|---|---|---|---|---|
| Participants/events | 23867/1031 | 5977/296 | 6098/250 | 5883/250 | 5909/235 |
| TC mg/dl, mean (SD) |
191.5 (39.0) | ||||
| LDL-C mg/dl, mean (SD)** |
114.1 (34.5) | 77.4 (16.6) | 102.1 (14.8) | 121.7 (16.0) | 155.8 (27.3) |
| HDL-C mg/dl, mean (SD)** |
52.2 (16.2) | 45.3 (12.9) | 51.1 (14.6) | 54.8 (16.4) | 58.0 (17.7) |
| Triglycerides mg/dl, mean (SD)** |
126.0 (63.8) | 111.9 (56.4) | 120.5 (60.0) | 127.3 (64.1) | 144.6 (69.7) |
| Non-HDL-C mg/dl, mean (SD)** |
139.2 (37.4) | 99.8 (17.3) | 126.2 (15.8) | 147.1 (17.6) | 184.8 (29.9) |
| Age in years, n (%)** |
64.7 (9.4) | 66.0 (9.6) | 64.9 (9.5) | 64.3 (9.3) | 63.6 (8.9) |
| Follow-up time (years), n (%)** |
7.5 (2.9) | 7.3 (3.0) | 7.6 (2.9) | 7.0 (2.6) | 7.5 (2.9) |
| Black, n (%)* | 9541 (40.0) | 2290 (38.3) | 2388 (39.2) | 2405 (40.9) | 2458 (41.6) |
| Male, n (%)* | 10726 (44.9) |
3621 (60.6) | 2894 (47.5) | 2359 (40.1) | 1852 (31.3) |
| Region, n (%) | |||||
| Belt | 8258 (34.6) | 2094 (35.0) | 2139 (35.1) | 2026 (34.4) | 1999 (33.8) |
| Buckle | 5060 (21.2) | 1329 (22.2) | 1264 (20.7) | 1237 (21.0) | 1230 (20.8) |
| Non-Belt | 10549 (44.2) |
2554 (42.8) | 2695 (44.2) | 2620 (44.5) | 2680(45.4) |
| Income, n (%)* | |||||
| <$20k | 3964 (16.6) | 959 (16.0) | 976 (16.0) | 990 (16.8) | 1039 (17.6) |
| $20kâ$35k | 5721 (24.0) | 1468 (24.6) | 1436 (23.6) | 1344 (22.9) | 1473 (24.9) |
| $35kâ$74k | 7413 (31.1) | 1901 (31.8) | 1948 (31.9) | 1853 (31.5) | 1711 (29.0) |
| $75k + | 4001 (16.8) | 996 (16.7) | 1043 (17.1) | 1004 (17.1) | 958 (16.2) |
| Refused | 2768 (11.6) | 653 (10.9) | 695 (11.4) | 692 (11.8) | 728 (12.3) |
| Education, n (%)* | |||||
| Less than HS | 2714 (11.4) | 770 (12.9) | 635 (10.4) | 656 (11.2) | 653 (11.1) |
| HS | 6131 (25.7) | 1537 (25.7) | 1511 (24.8) | 1460 (24.8) | 1623 (27.5) |
| Some College | 6397 (26.8) | 1515 (25.4) | 1644 (27.0) | 1609 (27.4) | 1629 (27.6) |
| College Grad and above |
8625 (36.1) | 2155 (36.1) | 2308 (37.9) | 2158 (36.7) | 2004 (33.9) |
| SBP** mmHg, mean (SD) |
127.1 (16.4) | 126.8 (16.1) | 127.0 (16.2) | 126.8 (16.6) | 127.6 (16.9) |
| Smoking, n (%)* | |||||
| Current | 3310 (13.9) | 842 (14.1) | 762 (12.5) | 794 (13.5) | 912 (15.4) |
| Never | 10981 (46.0) |
2496 (41.8) | 2846 (46.7) | 2811 (47.8) | 2828 (47.9) |
| Past | 9576 (40.1) | 2639 (44.2) | 2490 (40.8) | 2278 (38.7) | 2169 (36.7) |
| Hypertensive Meds, n (%)* |
12300 (51.5) |
3606 (60.3) | 3225 (52.9) | 2841 (48.3) | 2628 (44.5) |
| Lipid Lowering Meds, n (%)* |
7796 (32.7) | 2957 (49.5) | 2150 (35.3) | 1532 (26.0) | 1157 (19.6) |
| Atrial Fibrillation, n (%)* |
1936 (8.1) | 662 (11.1) | 476 (7.8) | 417 (7.1) | 381 (6.5) |
| Diabetes, n (%)* | 4727 (19.8) | 1813 (30.3) | 1233 (20.2) | 920 (15.6) | 761 (12.9) |
| LVH, n (%) | 2301 (9.6) | 564 (9.4) | 590 (9.7) | 546 (9.3) | 601 (10.2) |
| Heart Disease, n (%)* |
3899 (16.3) | 1665 (27.9) | 976 (16.0) | 692 (11.8) | 566 (9.6) |
*
Significant at the .05 level, Chi-Square test
**
Significant at the .05 level, ANOVA F-test
SD = standard deviation; LDL-C = low density lipoprotein cholesterol; HDL-C=high density lipoprotein cholesterol; HS=high school; SBP=systolic blood pressure; LVH=left ventricular hypertrophy