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. 2016 Aug 23;11:4077–4091. doi: 10.2147/IJN.S95767

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© 2016 Ling et al. This work is published and licensed by Dove Medical Press Limited

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Characterization of three-in-one multifunctional lipid-GcNa nanocarriers (TMLGNs).

Notes: (A) TEM. (B) Particle size distribution of TMLGNs. (C) DSC curves. (D) In vitro release profiles of MTO in pH 7.4 PBS containing 0.2% Na₂SO₃ from MTO-Sol, MTO-NLCs, and MTO-TMLGNs determined by the dialysis bag technique (mean ± SD, n=6).

Abbreviations: GcNa, sodium glycocholate; TEM, transmission electron microscopy; MTO, mitoxantrone hydrochloride; NLC, nanostructured lipid carrier; SD, standard deviation; DSC, differential scanning calorimetry; CsA, cyclosporine A; PBS, phosphate buffered saline.