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. 2016 Aug 23;11:4107–4124. doi: 10.2147/IJN.S110146

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© 2016 Li et al. This work is published and licensed by Dove Medical Press Limited

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The cytotoxicity of different drug loaded by macrophages.

Notes: (A) In vitro cytotoxicity of drugs/nanoparticles-loaded macrophages against the tumor cells observed under a microscope; in vitro cytotoxicity of drugs/nanoparticles-loaded macrophages against the MCF-7 cells (B) and MDA-MB-231 cells (C). Data are expressed as mean ± SD (n=5). *P<0.05. All the drugs were at the maximal dosage packaged in 30,000 macrophages/mL.

Abbreviations: DOX, doxorubicin; PTX, paclitaxel; SOC, N-succinyl-N′-octyl chitosan; SD, standard deviation.