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. Author manuscript; available in PMC: 2016 Aug 31.
Published in final edited form as: Cell Rep. 2016 Jul 21;16(5):1326–1338. doi: 10.1016/j.celrep.2016.06.076

Figure 6. E2 Residue 82 Influences Neutralization of CHIKV with Human Immune Sera.

Figure 6

(A–C and E–H) The neutralizing activity of human sera from CHIKV-immune subjects was quantified using PRNT50 analysis against the indicated viruses. (D and I) Non-immune human sera was included as a control. The serum dilutions at which 50% of AF15561 (red text), AF15561E2 G82R, SL15649 (grey text), or SL15649E2 G82R (blue text) were neutralized (PRNT50) were determined by non-linear regression (95% CI). Each graph represents the mean and standard deviation (SD) from two independent experiments.