Open field activity, weight gain, and corticosterone levels before and during repeated stress exposure for all rats. (A) Percent time in open field on day 0, (Baseline), day 1, and day 5 of TMT or saline exposure (****p<0.0001). (B) Total distance moved in an open field on day 0, (Baseline), day 1, and day 5 of TMT or saline exposure (****p<0.0001). (C) Weight gain of TMT-PE and Saline-PE rats on day 5 of TMT or saline exposure (****p<0.0001). (D) Corticosterone levels of TMT-PE and Saline-PE rats on day 0, (Baseline), day 1, and day 5. (****p<0.0001, ###p<0.001). Mean +/− SEM; n=32 rats per group)