Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In Vitro Potencies of Newly Synthesized Inhibitors with Modified Pyridone Core
| |||
|---|---|---|---|
| Cmpd | Structure | IC50(nM) | |
| EZH2 | EZH1 | ||
| 5 |
|
<10 | 69 ± 14 |
| 39 |
|
>10000 | >10000 |
| 40 |
|
>2300 | >10000 |
| 41 |
|
>10000 | >10000 |
| 42 |
|
>10000 | >10000 |
| 43 |
|
>10000 | >10000 |
