Table 3.
Predictive models with significant contributions from diffusion changes
| Dependent Variable | Parameter | Estimate | Standard Error | p-value |
|---|---|---|---|---|
| Univariate Models: | ||||
| ΔZ HVLT-PR at 6 months | Intercept | −0.046 | 0.31 | 0.88 |
| %Δ AD at mid-RT | 0.14 | 0.045 | 0.0054 | |
| ΔZ COWAT at 18 months | Intercept | 0.36 | 0.14 | 0.015 |
| %Δ RD at end-RT | −0.056 | 0.016 | 0.0018 | |
| Multivariate Model: | ||||
| ΔZ COWAT at 18 months | Intercept | 0.31 | 0.17 | 0.079 |
| %Δ RD at end-RT | −0.055 | 0.02 | 0.0023 | |
| Frontotemporal | 0.15 | 0.28 | 0.60 |
Parameter estimates reflect effect on cognitive Z-score change for 1% increase in diffusion variable, or for frontotemporal versus other tumor location.