Table 1.

Summary of clinical constraints used to generate and evaluate esophageal IMRT treatment plans, listed in order from highest to lowest planning priority in column 1. Columns 3–8 are a tabulation of the number of clinical plans “inside” versus “outside” and “better” versus “worse” than their corresponding predicted DVH bands at each of the clinical dose/volume evaluation points. Bolded and italicized values represent regional sites that statistically differed (p < 0.05) from MC for that metric.

		Location of Planned DVH Relative to Predicted Bounds		Inside Vs. Outside	Quality of Planned DVH Relative to Prediction		Better vs Worse
Organ / Criteria	Campus	# (%) inside	# (%) outside	p-value	# (%) better	# (%) worse	p-value
Lungs V20Gy ≤ 20%	MC	14 (50.0%)	14 (50.0%)		6 (42.9%)	8 (57.1%)
	RS1	25 (65.8%)	13 (34.2%)	0.217	8 (61.5%)	5 (38.5%)	0.450
	RS2	40 (69.0%)	18 (31.0%)	0.101	10 (55.6%)	8 (44.4%)	0.722
	RS3	16 (43.2%)	21 (56.8%)	0.311	5 (23.8%)	16 (76.2%)	0.283
	RS4	7 (63.6%)	4 (36.4%)	0.497	2 (50.0%)	2 (50.0%)	1.000
Lungs V30Gy ≤ 15%	MC	17 (60.7%)	11 (39.3%)		7 (63.6%)	4 (36.4%)
	RS1	20 (52.6%)	18 (47.4%)	0.618	11 (61.1%)	7 (38.9%)	1.000
	RS2	31 (53.4%)	27 (46.6%)	0.644	19 (70.4%)	8 (29.6%)	0.714
	RS3	16 (43.2%)	21 (56.8%)	0.213	12 (57.1%)	9 (42.9%)	1.000
	RS4	6 (54.5%)	5 (45.5%)	0.734	3 (60.0%)	2 (40.0%)	1.000
Lungs V40Gy ≤ 10%	MC	19 (67.9%)	9 (32.1%)		7 (77.8%)	2 (22.2%)
	RS1	20 (52.6%)	18 (47.4%)	0.311	10 (55.6%)	8 (44.4%)	0.406
	RS2	26 (44.8%)	32 (55.2%)	0.065	24 (75.0%)	8 (25.0%)	1.000
	RS3	15 (40.5%)	22 (59.5%)	0.045	15 (68.2%)	7 (31.8%)	0.689
	RS4	5 (45.5%)	6 (54.5%)	0.277	4 (66.7%)	2 (33.3%)	1.000
Heart V30Gy ≤ 20–30%	MC	15 (53.6%)	13 (46.4%)		8 (61.5%)	5 (38.5%)
	RS1	17 (44.7%)	21 (55.3%)	0.619	5 (23.8%)	16 (76.2%)	0.038
	RS2	32 (55.2%)	26 (44.8%)	1.000	13 (50.0%)	13 (50.0%)	0.734
	RS3	13 (35.1%)	24 (64.9%)	0.206	13 (54.2%)	11 (45.8%)	0.739
	RS4	2 (18.2%)	9 (81.8%)	0.073	4 (44.4%)	5 (55.6%)	0.666
Heart Mean ≥ 30 Gy	MC	22 (78.6%)	6 (21.4%)		1 (16.7%)	5 (83.3%)
	RS1	13 (34.2%)	25 (65.8%)	0.001	6 (24.0%)	19 (76.0%)	1.000
	RS2	39 (67.2%)	19 (32.8%)	0.321	8 (42.1%)	11 (57.9%)	0.364
	RS3	16 (43.2%)	21 (56.8%)	0.005	9 (42.9%)	12 (57.1%)	0.363
	RS4	7 (63.6%)	4 (36.4%)	0.424	2 (50.0%)	2 (50.0%)	0.500
Liver V20Gy ≤ 20–45%	MC	10 (35.7%)	18 (64.3%)		11 (61.1%)	7 (38.9%)
	RS1	8 (21.1%)	30 (78.9%)	0.264	15 (50.0%)	15 (50.0%)	0.555
	RS2	21 (36.2%)	37 (63.8%)	1.000	17 (45.9%)	20 (54.1%)	0.391
	RS3	13 (35.1%)	24 (64.9%)	1.000	12 (50.0%)	12 (50.0%)	0.542
	RS4	2 (18.2%)	9 (81.8%)	0.446	9 (100.0%)	0 (0.0%)	0.059
Liver V30Gy ≤ 20%	MC	13 (46.4%)	15 (53.6%)		9 (60.0%)	6 (40.0%)
	RS1	12 (31.6%)	26 (68.4%)	0.305	13 (50.0%)	13 (50.0%)	0.746
	RS2	25 (43.1%)	33 (56.9%)	0.819	19 (57.6%)	14 (42.4%)	1.000
	RS3	8 (21.6%)	29 (78.4%)	0.060	21 (72.4%)	8 (27.6%)	0.501
	RS4	1 (9.1%)	10 (90.9%)	0.060	8 (80.0%)	2 (20.0%)	0.402
Liver Mean ≤ 25 Gy	MC	19 (67.9%)	9 (32.1%)		4 (44.4%)	5 (55.6%)
	RS1	15 (39.5%)	23 (60.5%)	0.027	12 (52.2%)	11 (47.8%)	1.000
	RS2	34 (56.6%)	24 (41.4%)	0.482	10 (41.7%)	14 (58.3%)	1.000
	RS3	25 (67.6%)	12 (32.4%)	1.000	6 (50.0%)	6 (50.0%)	1.000
	RS4	6 (54.5%)	5 (45.5%)	0.478	4 (80.0%)	1 (20.0%)	0.301
Stomach Mean ≤ 30 Gy	MC	24 (85.7%)	4 (14.3%)		3 (75.0%)	1 (25.0%)
	RS1	18 (47.4%)	20 (52.6%)	0.002	6 (30.0%)	14 (70.0%)	0.130
	RS2	29 (50.0%)	29 (50.0%)	0.005	5 (17.2%)	24 (82.8%)	0.036
	RS3	16 (43.2%)	21 (56.8%)	0.001	9 (42.9%)	12 (57.1%)	0.322
	RS4	9 (81.8%)	2 (18.2%)	1.000	1 (50.0%)	1 (50.0%)	1.000
Lungs V10Gy ≤ 35–65%	MC	21 (75.0%)	7 (25.0%)		6 (85.7%)	1 (14.3%)
	RS1	18 (47.4%)	20 (52.6%)	0.042	10 (50.0%)	10 (50.0%)	0.183
	RS2	27 (46.6%)	31 (53.4%)	0.020	15 (48.4%)	16 (51.6%)	0.104
	RS3	14 (37.8%)	23 (62.2%)	0.005	17 (73.9%)	6 (26.1%)	1.000
	RS4	6 (54.5%)	5 (45.5%)	0.262	4 (80.0%)	1 (20.0%)	1.000