Table 2.
Tabulation of the number of plans “inside” versus “outside” and “better” versus “worse” than the gEUD predicted values for each organ at each campus. The following values of the parameter ‘a’ were chosen for the gEUD calculations: heart (1.6)[24], lungs (1.0)[25], and stomach (6.7)[25]. The liver is not included in this table because an a = 1.0 was recommended[26], but this corresponds to the mean dose shown in Table 1. Bolded and italicized values represent regional sites that statistically differed (p < 0.05) from MC for that metric. A patient is scored as “inside” if the planned gEUD was between the gEUDs of the upper and lower predicted bounds. For those that were outside the bounds, they were recorded as “better” if the planned gEUD was less than the lower predicted gEUD bound or “worse” if it was higher than the upper predicted gEUD bound.
gEUD Predicted bounds | Inside vs Outside | gEUD Predicted bounds | Better vs Worse | ||||
---|---|---|---|---|---|---|---|
| |||||||
Organ | Campus | # (%) inside | # (%) outside | p-value | # (%) better | # (%) worse | p-value |
Lungs (a = 1.0) | |||||||
MC | 24 (85.7%) | 4 (14.3%) | 2 (50.0%) | 2 (50.0%) | |||
RS1 | 29 (76.3%) | 9 (23.7%) | 0.533 | 6 (66.7%) | 3 (33.3%) | 1.000 | |
RS2 | 41 (70.7%) | 17 (29.3%) | 0.182 | 8 (47.1%) | 9 (52.9%) | 1.000 | |
RS3 | 24 (64.9%) | 13 (35.1%) | 0.087 | 9 (69.2%) | 4 (30.8%) | 0.584 | |
RS4 | 8 (72.7%) | 3 (27.3%) | 0.379 | 2 (66.7%) | 1 (33.3%) | 1.000 | |
| |||||||
Heart (a = 1.6) | |||||||
MC | 22 (78.6%) | 6 (21.4%) | 1 (16.7%) | 5 (83.3%) | |||
RS1 | 15 (39.5%) | 23 (60.5%) | 0.002 | 6 (26.1%) | 17 (73.9%) | 1.000 | |
RS2 | 39 (67.2%) | 19 (32.8%) | 0.321 | 8 (42.1%) | 11 (57.9%) | 0.364 | |
RS3 | 15 (40.5%) | 22 (59.5%) | 0.003 | 10 (45.5%) | 12 (54.5%) | 0.355 | |
RS4 | 5 (45.5%) | 6 (54.5%) | 0.062 | 3 (50.0%) | 3 (50.0%) | 0.546 | |
| |||||||
Stomach (a = 6.7) | |||||||
MC | 20 (71.4%) | 8 (28.6%) | 5 (62.5%) | 3 (37.5%) | |||
RS1 | 20 (52.6%) | 18 (47.4%) | 0.137 | 5 (27.8%) | 13 (72.2%) | 0.189 | |
RS2 | 43 (74.1%) | 15 (25.9%) | 0.800 | 2 (13.3%) | 13 (86.7%) | 0.026 | |
RS3 | 15 (40.5%) | 22 (59.5%) | 0.012 | 11 (50.0%) | 11 (50.0%) | 0.689 | |
RS4 | 7 (63.6%) | 4 (36.4%) | 0.708 | 1 (25.0%) | 3 (75.0%) | 0.546 |