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. Author manuscript; available in PMC: 2017 Feb 25.
Published in final edited form as: Nature. 2016 Aug 25;536(7617):474–478. doi: 10.1038/nature18952

Extended Data Figure 5. Protective efficacy of prM-Env DNA vaccine in C57BL/6 mice.

Extended Data Figure 5

C57BL/6 mice (N=5/group) received a single immunization by the i.m. route with 50 µg full-length prM-Env DNA vaccine or a sham vaccine and were challenged at week 4 by the i.v. route with 105 VP (102 PFU) ZIKV-BR or ZIKV-PR. Serum viral loads are shown following challenge.