Table 1. ZIKV-specific neutralizing antibody titers.

Balb/c mice received a single immunization with 50 µg of various DNA vaccines (Fig. 1–2) or 1 µg purified inactivated virus (PIV) vaccines with alum (Fig. 4), and pooled serum was assessed for ZIKV-specific neutralizing antibodies at week 4. 50% microneutralization (MN50) titers are shown. Also shown are MN50 titers in serum from mice following two immunizations with DNA-prM-Env (boost) and an anti-flavivirus human polyclonal antibody.

Vaccine	ZIKV MN50 Titer
DNA-prM-Env	22
DNA-prM-Env.dTM	<10
DNA-prM-Env.dStem	<10
DNA-Env	<10
DNA-Env.dTM	<10
DNA-Env.dStem	<10
DNA-prM-Env (boost)	1,022
PIV/alum i.m.	15
PIV/alum s.q.	15
Sham/alum i.m.	<10
Sham/alum s.q.	<10
Anti-flavivirus Ab	232