Table 2.

Distribution of High-grade Squamous Neoplasia for Selected Characteristics by Diethylstilbestrol Exposure Status

Characteristics	DES Exposed			DES Unexposed
	# person- years	%	# cases	# person- years	%	# cases
ALL	88098		145	35934		33
Cohort
DESAD	72915	82.8	98	19251	53.6	17
Dieckmann	6408	7.3	16	5695	15.9	8
Horne	5731	6.5	26	4326	12.0	3
WHS	3044	3.5	5	6663	18.5	5
Age (y; time-dependent)
<30	14548	16.5	41	4418	12.3	6
30–34	15110	17.2	41	5152	14.3	9
35–39	15710	17.8	26	5728	15.9	4
40–44	14083	16.0	21	5725	15.9	3
45–49	12146	13.8	6	5537	15.4	5
50+	16505	18.7	10	9377	26.1	6
Birth year
<1953	34732	39.4	48	18095	50.4	15
1953+	53366	60.6	97	17839	49.6	18
Calendar year (time-dependent)
<1995	44544	50.6	98	15373	42.8	17
1995+	43558	49.4	47	20565	57.2	16
Education (1994)
<4-year college	27170	30.8	48	13696	38.1	20
4-year college	30541	34.7	56	11487	32.0	5
Graduate school	23440	26.6	35	8849	24.6	7
Missing	6948	7.9	6	1902	5.3	1
Smoking status (at exit or 2006)
Never	45916	52.1	71	17087	47.5	6
Ever	38094	43.2	69	17589	49.0	25
Missing	4088	4.7	5	1261	3.5	2
Menopausal status (time-dependent)
Premenopausal	73103	83.0	138	28383	79.0	29
Postmenopausal	14503	16.5	6	7342	20.4	4
Missing	492	0.56	1	209	0.58	0
Age at first intercourse
<=18	36511	41.4	72	15642	43.5	16
19+	45167	51.3	67	17502	48.7	14
Missing	6420	7.3	6	2790	7.8	3
# of male partners (1994)
<5	42742	48.5	35	16779	46.7	8
5–9	17168	19.5	46	7948	22.1	9
10+	26102	29.6	59	9330	26.0	13
Missing	2086	2.4	5	1876	5.2	3
# of Pap smearsa
<3	18903	21.5	14	8286	23.1	6
3+	59436	67.5	101	23266	64.8	21
Missing	9760	11.1	30	4382	12.2	6

Abbreviations: High-grade Squamous Neoplasia, CIN2+; Diethylstilbestrol, DES.

^aReported for the 5 years before the most recent questionnaire.