Table 3.

Hazard Ratios and 95% Confidence Intervals for Prenatal Diethylstilbestrol Exposure and High-grade Squamous Neoplasia

	# Cases	HR	95% CI
DES
Adjusted for birth year & cohort	178	1.98	1.33	2.94
+ # of Pap smearsa	178	1.97	1.33	2.93
+ covariatesb	178	2.10	1.41	3.13
Slide confirmed cases onlyc	134	2.15	1.35	3.41
by Cohortd
DESAD	115	1.38	0.82	2.32
Dieckmann	24	1.82	0.78	4.25
Horne	29	6.88	2.06	23.0
WHS	10	2.08	0.60	7.23
by Agee
<30	47	2.66	1.11	6.37
30–34	50	1.97	0.94	4.15
35–39	30	2.87	0.98	8.42
40–44	24	3.11	0.88	11.0
45+	27	0.91	0.39	2.10

Abbreviations: Hazard Ratios, HR; 95% Confidence Intervals, CI; Diethylstilbestrol, DES; High-grade Squamous Neoplasia, CIN2+.

^aAdjusted for birth year, cohort and number of Pap smears over the last 5 years prior to the questionnaire before diagnosis or censoring.

^bIn addition to birth year, cohort and # of Pap smears, covariates include education, smoking, age at first sexual intercourse, and # of male sexual partners.

^cAdjusted for birth year and cohort.

^dAdjusted for birth year.

^eAdjusted for cohort.