Figure 4.

Melanoma cells increase HLA Class I and HLA-DR expression upon exposure to CTLs. Exposure of different melanoma cell lines to MelanA-specific CTLs (green) or CTL-derived cytokines (black) but not to non-specific CTLs (blue) provoked changes of protein expression on the melanoma cells. Untreated cells are shown in red. HLA Class I was calculated as fold-change compared to untreated cells. HLA-DR is presented as % positive of living cells. Measurements were performed by flow cytometry. N = 2, error bars indicate SD.