Table 1.
Comparative studies on identification of microorganisms using different MALDI-TOF MS platforms and databases from the time point of the published work.
| Organism (nos.) | MALDI-TOF MS system and database | Results | References |
|---|---|---|---|
| Bacteria from clinical sources (720) | Bruker Biotyper | High confidence identifications (94%) and incorrect identification (0.9%). | Cherkaoui et al., 2010 |
| Shimadzu MS with Saramis database | High confidence identifications (89%) and incorrect identification (0.5%). | ||
| Bacteria isolated in routine at hospital (317) | Bruker Biotyper (ver. 2.0) | Correct identification to genus level (97.4%) and species level (94.9%). | Carbonnelle et al., 2012 |
| Axima Assurance system Shimadzu/SARAMIS (Anagnos Tec GmbH ver. 2008) | Correct identification to genus level (97.2%) and species level (93.4%). | ||
| Selected bacterial strains with low discrimination with phenotypic tests, unusual antimicrobial susceptibility and fastidious cultures (296) | Bruker Biotyper (ver. 2.0) | Correct identification to genus level (94.9%) and species level (83.4%). | Carbonnelle et al., 2012 |
| Axima Assurance system Shimadzu/SARAMIS (Anagnos Tec GmbH ver. 2008) | Correct identification to genus level (83.8%) and species level (65.9%). | ||
| Non-fermenting Gram-negative bacilli isolated from cystic fibrosis (200) | Bruker Biotyper (ver. 3.0) | Overall identification (97%), including species level (72.5%), complex level (5.5%) and genus (19.0%), and no identification (3.0%). | Marko et al., 2012 |
| Vitek MS (SARAMIS ver. 3.62) | Overall identification (93%), including species level (80.0%), complex level (3.5%), genus (6.0%) and family (3.5), and no identification (7.0%). | ||
| Bacteria from multiple clinical sources (986) | Bruker Biotyper (ver. 3.0) | Genus and species level (92.7%), genus level (2.8%) and no identification (3.2%). Misidentification to species level (1.2%) and genus level (0%). | Martiny et al., 2012 |
| Vitek MS (IVD v1) | Genus and species level (93.2%), genus level (0.4%) and no identification (5.8%). Misidentification to species level (0.4%) and genus level (0.2%). | ||
| Vitek MS (Saramis database) | Genus and species level (83.8%), genus level (3.1%) and no identification (12.8%). Misidentification to species level (0.3%) and genus level (0%). | ||
| Yeasts isolated from routine clinical specimens (312) | Bruker Biflex III-Biotyper (ver. 2.0.4.0) | Valid identification (87.2%), correct species identification of < 1.7 (5.8%), no identification (6.4%) and false species identification (0.6%). | Lohmann et al., 2013 |
| Axima-SARAMIS (AnagnosTec ver. 4.07) | Valid identification (82.7%), correct species identification of < 40% (2.9%), no identification (13.1%) and false species identification (1.3%). |