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Timeline of major events in cGvHD research using animal models. Chronic GvHD is characterized by autoantibody production and deposition in target tissues, and tissue fibrosis. The timeline presents how animal models have contributed to increased understanding of the pathology of cGvHD, and included is also the NIH consensus reports on staging and diagnosis of cGvHD, which has contributed to development of improved rodent models of cGvHD during the last decade.
