. 2016 Aug 30;7:333. doi: 10.3389/fimmu.2016.00333

Table 1.

Overview of rodent models for acute GvHD.

Species	Model	MHC haplotype	Conditioning	MHC mismatch	Reference
Mouse	C57BL/6 → BALB/c	H2^b → H2^d	TBI	Complete	(27, 30, 52, 53)
	C3H/HeJ → C57BL/6	H2^k → H2^b
	C57BL/6 → B10.BR	H2^b → H2^k
	C57BL/6 → B6C3F1	H2^b → H2^k/b	TBI	Haploidentical	(54–58)
	C57BL/6 → B6D2F1	H2^b → H2^b/d
	C57BL/6 → B6AF1	H2^b → H2^b/a
	C57BL/6 → B6.C-H2^bm1	H2^b → H2^bm1	TBI or none	MHC-I	(59, 60)
	C57BL/6 → B6.C-H2^bm12	H2^b → H2^bm12	TBI or none	MHC-II	(59, 60)
	B10.D2 → DBA/2	H2^d → H2^d	TBI	miHA	(42, 43, 61–63)
	B10.D2 → BALB/c	H2^d → H2^d
	B10 → BALB.b	H2^b → H2^b
	C57BL/6→ BALB.b	H2^b → H2^b
	DBA/2 → B10.D2	H2^d → H2^d
Rat	BN → LEW	RT1ⁿ → RT1^l	TBI or CYP or anti-CD25/CD154/CTLA4 Ig	Complete	(45, 64–71)
	PVG → BN	RT1^c → RT1ⁿ
	DA → LEW	RT1^av1 → RT1^l
	LEW → BN	RT1^l → RT1ⁿ
	Wistar Furth → LEW	RT^1u → RT1^l
	LEW.1AR1 → LEW.1AR2	RT1A^a, RT1B/D^u, RT1C/E^u → RT1A^a, RT1B/D^a, RT1C/E^u	TBI	MHC-II	(72)
	BN → (BN × LEW) F₁	RT1ⁿ → RT1^n/l	TBI or none	Haploidentical	(47, 73)
	LEW → (LEW × BN) F₁	RT1^l → RT1^n/l			(48, 74–81)
	LEW → (LEW × DA) F₁	RT1^l → RT1^l/av1
	PVG → (PVG × DA) F₁	RT1^c → RT1^c/av1