Table 2.
Clinical presentation of hospitalized children with EV-D68.
| Clinical presentation | n (%) |
|---|---|
| Month of presentation (total n = 34) | |
| August | 1 (3) |
| September | 5 (15) |
| October | 25 (74) |
| November | 3 (9) |
|
| |
| Parent reported symptoms at presentation (total n = 34) | |
| Shortness of breath | 28 (82) |
| Cough | 28 (82) |
| Rhinorrhea/congestion | 24 (71) |
| Fever | 21 (62) |
| Wheeze | 15 (44) |
| Vomiting | 11 (32) |
|
| |
| Vital signs at presentation (total n = 34) | |
| Tachypnea∗ | 27 (79) |
| Tachycardia∗ | 20 (59) |
| Oxygen saturation <92% | 20 (59) |
| Fever ≥ 38°C | 4 (12) |
|
| |
| Auscultatory findings (total n = 34) | |
| Decreased air entry | 30 (88) |
| Wheeze | 26 (76) |
| Crackles | 12 (35) |
| Silent chest | 9 (26) |
|
| |
| PRAM score at presentation (total n = 22) | |
| 0–3 (mild) | 0 (0) |
| 4–7 (moderate) | 6 (27) |
| 8–12 (severe) | 16 (73) |
|
| |
| Laboratory findings (total n = 23) | |
| Leukocytosis∗∗ | 12 (52) |
| Neutrophilia∗∗ | 17 (74) |
| Lymphopenia∗∗ | 19 (83) |
|
| |
| Copathogens identified on PCR testing of nasopharyngeal washings (total n = 26) | 11 (42) |
|
| |
| Chest X-ray findings (total n = 29) | |
| Normal chest X-ray | 4 (14) |
| Minor patchy changes | 6 (21) |
| Major patchy changes | 6 (21) |
| Lobar changes | 1 (3) |
| Peribronchial thickening | 11 (38) |
| Hyperinflation | 9 (31) |
∗Vital sign parameters were defined according to norms for age as per the Hospital of Sick Children's Handbook of Pediatrics [15].
∗∗As defined by BCCH's laboratory reference values for age.