Table 3.

Content change trend of early cardiac toxicity biomarkers.

T R (min)	m/z	Metabolite	Content change
			Identified	HSP	GL	ZBM	BL	BJ	HSP + GL	HSP + ZBM	HSP + BL	HSP + BJ
0.76	162.1123	L-carnitine	↑	↑	↓	↑	↑	↓	↑	↑	↑	↑
4.19	190.0863		↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
4.19	172.0755		↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
4.19	130.065		↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
4.67	347.2214	19-Hydroxydeoxycorticosterone	↓	↓	↑	↓	↓	↓	↓	↓	↓	↓
5.45	432.3107		↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
5.87	299.2002		↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
7.30	468.3467		↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
7.85	548.3715	LPC (20:2)	↓	↓	↓	↓	↓	↓	↓	↓	↓	↓
6.48	490.2913	LPC (14:0)	↓	↓	↓	↓	↓	↓	↓	↓	↓	↓