Table 2.
V T values in all ROIs for Males versus Females. [11C] LY2795050 VT values calculated using the MA1 model. Values are shown for 19 ROIs and VND, with p-values for comparisons between M and F and AD and HC. Significant regions and values are in bold
| ROI | P-value | ||
|---|---|---|---|
|
|
|||
| M vs. F | M | F | |
| Whole Brain | 3.14 ± 0.38 | 2.89 ± 0.25 | 0.04 |
| Amygdala | 4.22 ± 0.68 | 4.06 ± 0.26 | 0.25 |
| Centrum Semiovale | 2.68 ± 0.41 | 2.56 ± 0.35 | 0.22 |
| Caudate | 2.54 ± 0.33 | 2.38 ± 0.29 | 0.11 |
| Cerebellum | 2.12 ± 0.34 | 1.94 ± 0.20 | 0.08 |
| Anterior Cingulate Cortex | 3.96 ± 0.51 | 3.43 ± 0.38 | 0.005 |
| Posterior Cingulate Cortex | 2.56 ± 0.28 | 2.41 ± 0.21 | 0.08 |
| Frontal Cortex | 3.59 ± 0.44 | 3.24 ± 0.29 | 0.02 |
| Hippocampus | 2.44 ± 0.33 | 2.37 ± 0.18 | 0.28 |
| Insula | 3.99 ± 0.52 | 3.61 ± 0.36 | 0.03 |
| Occipital Cortex | 3.09 ± 0.34 | 2.86 ± 0.28 | 0.15 |
| Ventral Pallidum | 3.64 ± 0.51 | 3.28 ± 0.50 | 0.04 |
| Parietal Cortex | 3.36 ± 0.42 | 3.09 ± 0.34 | 0.04 |
| Putamen | 3.42 ± 0.51 | 3.13 ± 0.32 | 0.07 |
| Temporal Cortex | 3.30 ± 0.39 | 3.03 ± 0.32 | 0.04 |
| Thalamus | 2.28 ± 0.29 | 2.29 ± 0.17 | 0.45 |
| Precentral Gyrus | 3.80 ± 0.50 | 3.34 ± 0.25 | 0.008 |
| Fusiform Gyrus | 2.68 ± 0.33 | 2.41 ± 0.28 | 0.02 |
| Rolandic Operator | 3.79 ± 0.47 | 3.40 ± 0.33 | 0.02 |
| VND | 1.56 ± 0.29 | 1.50 ± 0.27 | 0.75 |