Table 1.
The Gene Set Enrichment Analysis (GSEA) for pathways enriched in both UNC1999- and GSK343-treated HCT116 cells
Pathways | Number of Genes in Pathway | Number of Pathway Genes Differentially Expressed (% of Total) | p value |
---|---|---|---|
HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 81 | 18 (22%) | 0.000 |
HALLMARK_CHOLESTEROL_HOMEOSTASIS | 61 | 13 (21%) | 0.000 |
HALLMARK_MTORC1_SIGNALING | 148 | 27 (18%) | 0.500 |
HALLMARK_PI3K_AKT_MTOR_SIGNALING | 72 | 7 (10%) | 0.125 |