Table 5.
Expression and distribution of validated plasma membrane proteins in tumor and normal breast tissues
| Type of tissue | Protein | Intensitya | Cells stainedb | Locationc |
|---|---|---|---|---|
| IBC | C1QBP | 1/17: Weak | 14/17: +++ | 14/17: C |
| 5/17: Moderate | ||||
| 8/17: Strong | ||||
| 3/17: NTT | ||||
| L1CAM | 8/17: Weak | 8/17: + | 9/17: C | |
| 1/17: Moderate | 1/17: ++ | |||
| 6/17: NS | ||||
| 2/17: NTT | ||||
| MCAM | 4/17: Weak | 1/17: + | 2/17: C | |
| 10/17: NS | 3/17: +++ | 2/17: MC | ||
| 3/17: NTT | ||||
| MST1R | 6/17: Weak | 2/17: + | 3/17: C | |
| 8/17: Moderate | 2/17: ++ | 10/17: NC | ||
| 1/17: Strong | 11/17: +++ | 1/17: MC | ||
| 2/17: NTT | 1/17: M | |||
| MTDH | 6/15: Weak | 1/15: + | 14/15: C | |
| 4/15: Moderate | 13/15: +++ | |||
| 4/15: Strong | ||||
| 1/15: NTT | ||||
| PLGRKT | 4/17: Weak | 1/17: + | 8/17: C | |
| 4/17: Moderate | 3/17: ++ | 4/17: NC | ||
| 4/17: Strong | 8/17: +++ | |||
| 1/17: NS | ||||
| 4/17: NTT | ||||
| SCAMP3 | 12/17: Weak | 9/17: + | 9/17: C | |
| 2/17: NS | 1/17: ++ | 1/17: NC | ||
| 3/17: NTT | 2/17: +++ | 2/17: M | ||
| Control | C1QBP | 10/10: Weak | 10/10: +++ | 10/10: C |
| L1CAM | 10/10: NS | _ | _ | |
| MCAM | 10/10: Weak | 4/10: + | 9/10: C | |
| 1/10: ++ | 1/10: MC | |||
| 5/10: +++ | ||||
| MST1R | 8/10: Weak | 9/10: +++ | 9/10: NC | |
| 1/10: Moderate | ||||
| 1/10: NS | ||||
| MTDH | 10/10: Moderate | 10/10: +++ | 10/10: NC | |
| PLGRKT | 10/10: Moderate | 10/10: +++ | 10/10: NC | |
| SCAMP3 | 10/10: NS | _ | _ | |
| DC | C1QBP | 5/17: Weak | 17/17: +++ | 17/17: C |
| 6/17: Moderate | ||||
| 6/17: Strong | ||||
| L1CAM | 8/18: Weak | 4/18: + | 8/18: C | |
| 2/18: Moderate | 5/18: ++ | 1/18: MC | ||
| 6/18: NS | 1/18: +++ | 1/18: M | ||
| 2/18: NTT | ||||
| MCAM | 17/17: NS | _ | _ | |
| MST1R | 12/17: Weak | 1/17: + | 12/17: C | |
| 3/17: Moderate | 2/17: ++ | 2/17: NC | ||
| 1/17: Strong | 13/17: +++ | 2/17: MC | ||
| 1/17: NS | ||||
| MTDH | 7/17: Weak | 16/17: +++ | 16/17: C | |
| 9/17: Moderate | ||||
| 1/17: NTT | ||||
| PLGRKT | 12/17: Weak | 2/17: + | 9/17: C | |
| 1/17: Moderate | 2/17: ++ | 4/17: NC | ||
| 4/17: NS | 9/17: +++ | |||
| SCAMP3 | 10/19: NS | 5/17: + | 8/17: C | |
| 8/19: Weak | 1/17: ++ | |||
| 1/19: NTT | 2/17: +++ |
NS = no staining, NTT = no tumor tissue. “+” = Less than 10% cells positive staining, “++” = 10-50% cells positive staining, “+++” = More than 50% cells positive staining. C, NC, MC, M means cytoplasmic, nuclear and cytoplasmic, membranous and cytoplasmic, and membranous, respectively.