Table 1.
Association of DEC2 or E-cadherin expression with the clinicopathological characteristics of GC
| Characteristics | Case (49) | DEC2 expression | P value | E-cadherin expression | P value | ||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| High (11) | Low (38) | High (13) | Low (36) | ||||
| Age (years) | |||||||
| ≤50 | 7 | 2 | 5 | 0.646 | 2 | 5 | 0.608 |
| >50 | 42 | 9 | 33 | 11 | 31 | ||
| Gender | |||||||
| Female | 15 | 4 | 11 | 0.716 | 8 | 7 | 0.011* |
| Male | 34 | 7 | 27 | 5 | 29 | ||
| Tumor size (diameter) | |||||||
| ≤4 | 22 | 7 | 15 | 0.185 | 8 | 14 | 0.202 |
| >4 | 27 | 4 | 23 | 5 | 22 | ||
| Differentiation | |||||||
| I | 32 | 8 | 24 | 0.725 | 9 | 23 | 0.504 |
| II-III | 17 | 3 | 14 | 4 | 13 | ||
| Tumor invasion (AJCC) | |||||||
| T1-T2 | 14 | 8 | 6 | 0.001* | 9 | 5 | 0.000* |
| T3-T4 | 35 | 3 | 32 | 4 | 31 | ||
| Lymphatic metastasis | |||||||
| Absent | 17 | 7 | 10 | 0.033* | 8 | 9 | 0.038* |
| Present | 32 | 4 | 28 | 5 | 27 | ||
| TNM stage | |||||||
| I-II | 23 | 10 | 13 | 0.001* | 10 | 13 | 0.021* |
| III-IV | 26 | 1 | 25 | 3 | 23 | ||
*
Statistically significant difference; AJCC, American Joint Committee on Cancer.