Table 2. Univariate analysis - clinical, demographic, operative, and perioperative data of patients undergoing Partial Nephrectomy with only parenchymal suture vs: parenchymal suture with hemostatic agents and SURGICEL, suture with only HA and sutures with only SURGICEL.
| Variable | Sutures alone(n = 147) | Sutures and HA(n = 26) | P value | Sutures and SURGICEL(n = 183) | P value |
|---|---|---|---|---|---|
| Age (years) | 58.7 ± 13.5 | 64.3 ± 9.7 | 0.112 | 61.6 ± 13.5 | 0.887 |
| Gender | |||||
| Male | 97 (66) | 19 (73.1) | 0.761 | 117 (63.9) | 0.698 |
| Female | 50 (34) | 7 (26.9) | 66 (36.1) | ||
| BMI | 26.1 ± 5.6 | 25.9 ± 4.02 | 0.164 | 27.7 ± 4.7 | 0.612 |
| Mass location | |||||
| Upper Pole | 42 (28.6) | 3 (11.5) | 0.071 | 53 (29) | 0.135 |
| Middle aspect | 22 (15) | 5 (19.2) | 38 (20.8) | ||
| Lower Pole | 38 (25.9) | 12 (46.2) | 55 (30.1) | ||
| Mixed | 45 (30.6) | 6 (23.1) | 37 (20.2) | ||
| Multifocal mass | 16 (10.9) | 3 (11.5) | 0.922 | 32 (17.5) | 0.091 |
| Kidney side | |||||
| Left Kidney | 71 (48.3) | 16 (61.5) | 0.213 | 87 (47.5) | 0.887 |
| Right Kidney | 76 (51.7) | 10 (38.5) | 96 (52.5) | ||
| Central renal lesion | 35 (23.8) | 9 (34.6) | 0.243 | 79 (43.2) | <0.001 |
| Hilar renal lesion | 16 (10.9) | 3 (11.5) | 0.922 | 31 (16.9) | 0.118 |
| Mass size | 3.01 ± 1.43 | 2.47 ± 1.1 | 0.727 | 3.83 ± 1.62 | 0.003 |
| <4 cm | 135 (91.8) | 24 (92,3) | 117 (63.9) | ||
| >4 cm | 12 (8.2) | 2 (7.7) | 66 (36.1) | ||
| Pathology | |||||
| Malignant (RCC) | 104 (70.7) | 20 (76.9) | 0.59 | 140 (76.5) | 0.61 |
| Non-malignant* | 43 (29.3) | 6 (23.1) | 43 (23.5) | ||
| Operative method | |||||
| Open | 54 (36.7) | 5 (19.2) | 0.083 | 164 (89.6) | <0.001 |
| Laparoscopic | 93 (63.3) | 21 (80.8) | 19 (10.4) | ||
| Renal vascular clamping | |||||
| Yes | 107 (72.8) | 21 (80.8) | 0.393 | 127 (69.4) | 0.004 |
| No | 40 (27.2) | 5 (19.2) | 56 (30.6) | ||
| Ischemia Time (min) | 19.7 ± 10.9 | 14.5 ± 8.5 | 0.283 | 15.8 ± 10.6 | 0.87 |
| Preoperative HB (g/dL) | 13.6 ± 1.5 | 13.8 ± 1.1 | 0.09 | 13.5 ± 1.55 | 0.899 |
| Discharge HB (g/dL) | 11.4 ± 1.5 | 11.8 ± 1.5 | 0.845 | 11.45 ± 1.35 | 0.261 |
| PBT | 6 (4.1) | 2 (7.7) | 0.419 | 35 (19.1) | <0.001 |
| Leak | 1 (0.7) | 0 (0) | 0.673 | 9 (4.9) | 0.026 |
| Delayed bleeding | |||||
| Hematuria | 3 (2.04) | 1 (3.8) | 0.576 | 2 (1.6) | 0.867 |
| Flank hematoma | 0 (0) | 0 (0) | 0.773 | 1 (0.5) | NA |
| Pseudoaneurysm | 1 (0.7) | 0 (0) | NA | 5 (2.7) | 0.836 |
| Renal Failure | 3 (2.04) | 0 (0) | NA | 6 (3.3) | 0.718 |
| DVT/PE | 0 (0) | 1 (3.8) | NA | 3 (0.55) | NA |
Values in parentheses are percentages; Abbreviations: PBT = Perioperative blood transfusion; BMI = Body Mass Index; HB = Hemoglobin; RCC = Renal Cell Carcinoma; HA = Hemostatic agents; DVT = deep vein thrombosis; PE = pulmonary embolism. *Angiomyolipoma (AML), Oncocytoma, simple cyst.