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. 2016 Aug 30;6:32281. doi: 10.1038/srep32281

Table 2. In vitro activity of 15 antimicrobial agents against 248 FQ-resistant bacteremia E. coli isolates.

Antibiotica MIC (μg/mL)
% Susceptibility
Range MIC50 MIC90 S I R
Ampicillinb 6.0 1.2 92.8
Ampicillin-sulbactamb 42.0 17.0 41.0
Ceftazidime 0.06–>256 1 256 63.7 1.6 34.7
Cefepime <0.03–>256 0.12 4 91.5 3.2 5.3
Cefotaxime <0.03–>256 0.25 64 59.3 1.6 39.1
Cefoxitin 0.12–>256 8 256 54.0 1.6 44.4
Imipenem 0.12–>256 0.25 0.5 96.0 2.8 1.2
Meropenem <0.03–>128 <0.03 0.06 98.8 0 1.2
Amikacin 1–>256 4 8 98.0 0.4 1.6
Gentamicinb 54.0 3.6 42.4
Kanamycin 2–>256 16 >256 68.1 5.6 26.3
Tetracycline 1–>256 128 256 26.2 0.4 73.4
Fosfomycin 0.25–>256 1 2 99.6 0 0.4
Ciprofloxacin 0.12–>256 32 128 0 1.6 98.4
Levofloxacin 4–128 16 64 0 3.6 96.4

MIC50/90, minimum inhibitory concentration for 50% and 90% of the isolates, respectively; S, susceptible; I, intermediate resistant; R, resistant.

aOne isolate was resistant to tigecycline, and all isolates were susceptible to colistin.

bAntimicrobial susceptibilities of ampicillin, ampicillin-sulbactam, and gentamicin were determined by the disk diffusion method.