Table 1. Genotyping results for each estimated ABCG2 function of participants.
| Estimated ABCG2 function | Rs72552713 (Q126X) | Rs2231142 (Q141K) | Diplotype* | Number of participants |
||
|---|---|---|---|---|---|---|
| Hemodialysis | Health examination† | Acute gastroenteritis | ||||
| Full function | C/C | C/C | *1/*1 | 51 | 50 | 29 |
| 3/4 function | C/C | C/A | *1/*2 | 46 | 41 | 30 |
| 1/2 function | C/C | A/A | *2/*2 | 4 | 8 | 7 |
| C/T | C/C | *1/*3 | 3 | 5 | 1 | |
| ≤1/4 function | C/T | A/C | *2/*3 | 2 | 2 | 0 |
| T/T | C/C | *3/*3 | 0 | 0 | 0 | |
| Total | 106 | 106 | 67 | |||
**1, *2 and *3 represent haplotypes “C-C” (126Q and 141Q), “C-A” (126Q and 141K) and “T-C” (126X and 141Q) of two dysfunctional variants, Q126X (rs72552713) and Q141K (rs2231142), respectively.
†106 health examination participants were matched for sex- and body-mass index to 106 hemodialysis patients and selected from J-MICC Study.