Table 3. Dehydration in acute gastroenteritis patients for each ABCG2 function.

Estimated ABCG2 function (Diplotype of Q126X and Q141K)*	Number			P value‡
	Acute gastroenteritis	Dehydration†
		−	+
Full function (*1/*1)	29	23	6
3/4 function (*1/*2)	30	20	10
≤1/2 function (*1/*3, *2/*2, *2/*3 or *3/*3)	8	6	2
Total	67	49	18	0.50

^**1, *2 and *3 represent haplotypes of two dysfunctional variants (Q126X and Q141K). Detailed information on ABCG2 haplotypes is also shown in Table 1.

^†“−” means minimal or no dehydration and “+” means mild to moderate or severe dehydration evaluated according to the criteria recommended by the Center for Disease Control (CDC).

^‡P values were obtained by Cochran-Armitage test.