Figure 1.

(A) Map de Bruijn graph contigs to the long reads. The long reads are in red, the de Bruijn graph contigs are in other colors. Each long read is converted into an ordered list of contigs, termed compressed reads. (B) Calculate overlaps between the compressed reads. The alignment is calculated using the anchors. Contained reads are removed and the reads are chained together in the best-overlap fashion. (C) Layout: construct the assembly backbone from the best overlaps. (D) Consensus: align all related reads to the backbone and calculate the most likely sequence as the consensus output.