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| Tumour growth parameters | Model values |
|---|---|
| Input parameters | |
| Length of S phase | 11 h17 |
| Mean cell cycle time (range) | 33 h (20 – 60h)19 |
| Duration (proportions) of cell cycle phases | M:7%; G1:40%; S:30%; G2:23%17 |
| Cell loss factor | 85%19 |
| Model-derived parameters | |
| Volume doubling time | 52 d20 |
| Labelling index | 4.7%21 |
| Cell division rate (24h) | 1.3% |
| Pre-treatment probability of CSC symmetrical division | 1.9% |
| Pre-treatment percentage of CSCs | 5.42% |
