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. 2016 Aug 30;6:32121. doi: 10.1038/srep32121

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Copyright © 2016, The Author(s)

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Concentration-response curve on K_v1.2 and K_v1.6 channels obtained by plotting the percentage of blocked current as a function of increasing toxin concentrations. All data represent at least 3 independent experiments (n ≥ 3) and are presented as mean ± standard error. For both K_v1.2 and K_v1.6 channels it can be concluded that the amino acid substitutions K33A and G36N result in a decreased efficacy and in lower IC50 values, respectively.