Table 4. Data on BKV and BKN.
| BKV group (n = 86) | |
|---|---|
| BK viremia >7.000 | 46 (53.5%) |
| time from RTx until BKV pos (months) | 6 (0–36) |
| initial BK viral load of BKV patients without BKN | 4,334 (91–2,700,000) |
| maximum BK viral load of BKV patients without BKN | 18,572 (91–3,100,000) |
| initial BK viral load of all BKV patients | 5,540 (91–8,600,000) |
| maximum BK viral load of all BKV patients | 25,446 (91–196,000,000) |
| patients on Tac prolonged release (Advagraf) | 7 |
| patients on MMF at BKV | 44 |
| MMF dose at initial BKV infection | 1000 (500-2000) |
| Data of BKV patients with BKN (n = 8) | |
| Tac mean trough level (ng/ml) at time of BKN (n = 7) | 7.8 ± 2.6 |
| Tac mean daily dose (mg) at time of BKN (n = 7) | 9.0 (3.0–15.0) |
| Tac C/D ratio (ng/mL*1/mg) at time of BKN (n = 7) | 0.78 (0.33–2.47) |
| log Tac C/D ratio (log(ng/mL*1/mg)) at time of BKN (n = 7) | −0.24 (−1.12–0.90) |
| prednisolone mean daily dose (mg) at time of BKN (n = 6) | 10 (5–20) |
| initial BK viral load (n = 7) | 37,627 (850–8,600,000) |
| maximum BK viral load (n = 7) | 441,700 (41,144–196,000,000) |
Results are reported as absolute and relative frequencies, mean ± standard deviation or median (minimum-maximum). Abbreviations: BKV, BK virus; BKN, BK virus-associated nephropathy; viral load stated in copies/mL; Tac, tacrolimus; MMF, mycopheonolate mofetil.