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. 2016 Aug 30;6:32232. doi: 10.1038/srep32232

Table 1. Dysregulated miRNAs, genes and targeted pathways in MDS.

miRNA Style Fold change (MDS/control) Gene symbol Pathway
miR-148a Down −7.70 TEK PI3K-Akt signaling pathway
ITGA9 PI3K-Akt signaling pathway
KIT PI3K-Akt signaling pathway
HMGA2 Transcriptional misregulation in cancer
miR-145 Down −2.96 HHEX Transcriptional misregulation in cancer
MEIS1 Transcriptional misregulation in cancer
miR-200c Down −2.82 EFNA1 PI3K-Akt signaling pathway
KLF3 Transcriptional misregulation in cancer
miR-195 Up 6.04 BDNF MAPK signaling pathway
CDC25B MAPK signaling pathway
DLL1 Notch signaling pathway
MRAS MAPK signaling pathway
miR-17 Up 3.32 CAMK2D Calcium signaling pathway
miR-19a Up 5.85 MAML1 Notch signaling pathway
SLC8A1 Calcium signaling pathway
THBS1 Proteoglycans in cancer
TNF MAPK signaling pathway
TNFRSF1B Adipocytokine signaling pathway
ACSL1 Adipocytokine signaling pathway
EDNRB Calcium signaling pathway
miR-19b Up 2.53 CALM1 Calcium signaling pathway
TNF Proteoglycans in cancer