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. 2016 Aug 30;16(1):52. doi: 10.1186/s12894-016-0171-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Forest plot of the association between CDH13 methylation and tumor grade from a fixed-effects model, including 4 studies with 169 high-grade patients and 284 low-grade patients, OR = 2.22, 95 % CI = 1.72–6.80, P < 0.001