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. 2016 Aug 30;16(1):692. doi: 10.1186/s12885-016-2720-4

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — WES metrics comparison. Mean percentage ± SD (n = 5) of mapped, properly paired and duplicated reads obtained for each exome capture technology in both FF and FFPE libraries (a). Mean percentage ± SD (n = 5) of target bases achieving a certain coverage value or higher for each library type suggests that Roche kit tends to accumulate reads in low coverage regions (b). Mean percentage ± SD (n = 5) of on target bases for each library type. On target bases are referred to the number of aligned bases that map either on or near a bait within a 100 bp interval (c)