Skip to main content
. 2016 Aug 2;4(3):350–361. doi: 10.1002/iid3.118

Figure 3.

Figure 3

LXR‐deficient mice show decreased type 2 cytokine and chemokine levels in the lungs as compared to wild‐type (WT) mice in OVA‐ and house dust mite (HDM)‐induced asthma. (A) Cytokine and (B) chemokine levels in the bronchoalveolar lavage fluid (BALF) of WT and LXRα−/−β−/− mice after 2 consecutive OVA aerosols. (C) Cytokine and (D) chemokine levels in the BALF of WT and LXRα−/−β−/− mice after four intranasal HDM challenges. Cytokine and chemokine levels were determined by luminex analysis or ELISA. Data are shown as mean ± SD, n = 5–7 mice per group. The results show one representative experiment out of two independent experiments. Statistical analysis between two groups was performed using a Mann–Whitney U test. Significant P‐values were ranked as P < 0.05 (*) and P < 0.01 (**).