. 2016 Sep;148(3):239–251. doi: 10.1085/jgp.201611598

Table 3. Absolute Si influx and Pf values for wild-type and mutant channels.

Channels	Si influx	Water permeability	Expression
	nmol/oocyte/h	cm/s × 10⁻³	relative units
AQP1	0.39 ± 0.08	4.027 ± 0.578	1.00 ± 0.00
AQP1_{LGNRD↔IFATY}	0.37 ± 0.06	0.214 ± 0.148^a	0.90 ± 0.27^a
AQP1_L84C	0.37 ± 0.09	0.957 ± 0.333^a	0.91 ± 0.20^a
AQP1_Y186N	2.60 ± 0.59^a	3.624 ± 0.149	0.92 ± 0.04^a
AQP1_F56G/H180G	2.17 ± 0.36^a	3.844 ± 0.800	0.94 ± 0.03
AQP10	5.53 ± 0.79	0.060 ± 0.012	1.00 ± 0.00
AQP10_{IFATY↔LGNRD}	0.63 ± 0.28^b	0.071 ± 0.001	0.99 ± 0.07
AQP10_C90L	5.43 ± 1.79	0.254 ± 0.028^b	0.93 ± 0.06^b
AQP10_N208Y	2.13 ± 0.71^b	0.076 ± 0.003	1.10 ± 0.26
AQP10_G62F/G202H	2.27 ± 0.43^b	0.090 ± 0.021	1.39 ± 0.21^b

Values shown correspond to background-subtracted data, that is, data obtained in AQP-expressing oocytes − data obtained in water-injected oocytes. In the expression experiments, background-subtracted data were divided further by the quantity of channels present at the surface of AQP1- or AQP10-expressing oocytes. For all of the mutants, data are expressed as means ± SE of 3–10 oocytes among three to six experiments.

Data are significantly different statistically (P < 0.05) compared with AQP1-expressing oocytes.

Data are significantly different statistically (P < 0.05) compared with AQP10-expressing oocytes.