Figure 7.
IFNα expression directly regulates the expression of B-cell fate transcription factors. (A and B) Bar graphs showing the expression of genes involved in the modulation of lineage choice in LK cells obtained from C57/BL6 mice and treated ex vivo for 8 h (A) or three days (B) with 0.5 U/μL of recombinant murine-IFNα. Data are shown as log2 of the ratio between IFNα treated and control cells. Value are means, n=4. Results are expressed as the mean+SD. Statistical significance was determined by Student t-test (*P≤0.05; **P≤0.01; ***P≤0.001).