TABLE 1.

Hippocampal volume and memory task performance in children of mothers with hypothyroidism during pregnancy and children of control mothers¹

	Hypothyroid	Control	P
Hippocampal volumes, mm3
Total right hippocampus	1828 ± 264	1982 ± 244	0.012
Total left hippocampus	1728 ± 239	1862 ± 218	0.019
Memory task performance over a delay in hypothyroid and control groups
CMS dot locations
Short-delay recall2	10.2 ± 2.8	10.9 ± 2.9	NS
Long-delay recall2	10.4 ± 3.0	11.3 ± 2.8	NS
CMS stories: delayed recall2	12.0 ± 2.1	12.3 ± 2.8	NS
TML word selective reminding, delayed2	10.0 ± 2.5	10.4 ± 1.5	NS
TML visual selective reminding, delayed2	10.3 ± 1.5	10.4 ± 1.6	NS
TML face memory, delayed2	10.3 ± 1.4	10.9 ± 1.3	NS
Rey-Osterrieth, delayed recall3	14.5 ± 6.5	14.8 ± 5.5	NS
BRIEF working memory3	17.7 ± 5.9	14.4 ± 4.9	0.04
EMQ total3	49.9 ± 18.2	66.2 ± 30.4	0.04

¹Values are means ± SDs. Data are from reference 30. BRIEF, Behavioral Rating Inventory of Executive Function; CMS, Children’s Memory Scale; EMQ, Everyday Memory Questionnaire; TML, Test of Memory and Learning.

²Presented as scale scores.

³Presented as raw scores.