Histogram shows the composition of mtDNA macrohaplogroups in the study sample. Macrohaplogroups define major human lineages consisting of closely related haplogroups (Supplementary Fig. S2, http://links.lww.com/QAD/A542). In the present study sample, L1* comprised two common mtDNA haplogroups (L1b and L1c), L2* (L2a, L2b and L2e) and L3* (L3b, L3d, L3e, L3f, L3h and L3x). The non-L macrohaplogroups comprised other mtDNA haplogroups as indicated in Fig. S2. mtDNA, mitochondrial DNA; REACH, Reaching for Excellence in Adolescent Care and Health.