Table 4.

Biomarker comparison of urine sCD163 with urine PCR and combination sCD163/PCR for discriminating active renal vasculitis from remission

Comparator Variable	AUC	Cutoff	Sensitivity	Specificity	PPV	NPV	PLR	NLR
sCD163 normalized	0.91	0.3	0.83	0.97	0.89	0.95	30.6	0.17
PCR	0.68	15	0.97	0.39	0.3	0.97	1.6	0.08
sCD163+PCR	0.93		0.8	0.97	0.89	0.95	29.33	0.21
Bootstrap P-value	0.07

Statistics were determined by analyzing data from a subset of cases from the combined cohort. The bootstrap test compared the AUC sCD163 and PCR. AUC, area under curve; PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio.