Table 1.
White Participants | Black APOL1 Low-Risk Participants | Black APOL1 High-Risk Participants | |
---|---|---|---|
N | 11,464 | 3206 | 470 |
% | 75.7 | 21.2 | 3.1 |
Age, yr (mean) | 54.9 | 54.0a | 53.5a |
Female, % | 52.7 | 62.1a | 63.2a |
Body mass index, kg/m2 (mean) | 27.0 | 29.6a | 29.6a |
Systolic BP, mmHg (mean) | 118.5 | 128.3a | 128.9a |
Diabetes, % | 7.2 | 17.2a | 16.6a |
Hypertension, % | 27.3 | 55.0a | 57.1a |
Prior CHD event, % | 5.3 | 3.9a | 4.8 |
eGFRcr, ml/min per 1.73 m2 (mean) | 99.4 | 111.2a | 110.4a |
eGFRcr<60 ml/min per 1.73 m2, % | 1.0 | 2.1a | 2.3a |
LDL cholesterol, mg/dl (mean) | 137.7 | 138.0 | 135.3 |
HDL, mg/dl (mean) | 50.4 | 54.9a | 55.6a |
Triglycerides, mg/dl (mean) | 138.1 | 114.8a | 108.9a |
On aspirin, % | 52.7 | 29.4a | 31.0a |
On statin, % | 0.7 | 0.3a | 0.4 |
Smoking status | |||
Current, % | 24.7 | 29.4a | 33.6a |
Former, % | 35.4 | 24.2a | 22.5a |
Never, % | 39.9 | 46.2a | 43.9a |
Annual family income <$25,000, % | 25.4 | 63.3a | 64.4a |
Non-high school graduate, % | 17.1 | 40.2a | 42.8a |
CHD, coronary heart disease; eGFRcr, eGFR based on creatinine.
P<0.05 for comparison with the white subgroup. There were no statistically significant differences between blacks by APOL1 risk group.