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. 2016 Jul 15;15(17):2256–2262. doi: 10.1080/15384101.2016.1208872

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© 2016 INSERM - Institut Curie. Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 3. — Comparison of multiple markers vs. single proliferation marker to adjust for the impact of cell proliferation. Kaplan-Meier plots of breast cancer specific survival for patients of the METABRIC cohort having primary tumors with high (above median) or low (under median) ORC6 transcript levels before (left) and after adjustment of its expression with Ki67 (middle) or the proliferation metagene (right). Hazard ratio (HR) between highest and lowest survival groups and p-value of the Log-rank (Mantel-Cox) test are displayed on the plots.