Table 1.
Parameters in orthotopic bladder tumor model with and without intravesical therapy.
| Control | GFW | BCG | Mito-C | PBS | Pa | |
|---|---|---|---|---|---|---|
| Hematuria began (days postimplantation) | 9.6 ± 1 | 9.3 ± 0.8 | 9.9 ± 0.4 | 9.0 ± 0 | 9.6 ± 1 | 0.1854 |
| Hematuria ended (days postimplantation) | >22 | 17 | >25 | >22 | >22 | |
| Body weight (g) at the beginning | 21.7 ± 2.5 | 21.9 ± 1.8 | 22.8 ± 3.4 | 20.7 ± 1.3 | 20.2 ± 1.6 | 0.2515 |
| Body weight (g) at the end | 19.0 ± 3.9 | 22.7 ± 1.2 | 20.5 ± 2.9 | 20.3 ± 1.6 | 19.7 ± 1.3 | 0.0774 |
| Bladder volume (mm3) at the end | 445.1 ± 208 | 95.1 ± 66 | 168.7 ± 123.3 | 51.9 ± 38.6 | 371.7 ± 335.1 | 0.0012 |
| Animals with tumor cells identified in bladderb | 7 (7) | 1 (7) | 7 (7) | 2 (7) | 7 (7) |
a
ANOVA.
b
Number of test animals indicated in parentheses.