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. 2016 Jan 7;22:85–98. doi: 10.2119/molmed.2015.00199

Table 4B.

Equation of the multivariate model with a high predictive value for the factors related to COPD in LC patients.a

Pi = 1/1 + e–[–1.162 + (2.801 · protein carbonylation) + (1.796 · nitrotyrosine)]
a

Excluding patients with superoxide anion >3.56 nmol/L (because all of them are always LC-COPD, specificity 100%), a multivariate model with a high predictive value for the factors related to COPD in LC patients was obtained when protein carbonylation and nitrotyrosine were analyzed together. Pi is the probability of underlying COPD in patients with LC, e is the Euler’s number, protein carbonylation = 0, if levels of protein carbonylation are below 0.56 nmol/mg, or protein carbonylation = 1 when levels are equal or above 0.56 nmol/mg and nitrotyrosine = 0, if levels of nitrotyrosine are equal or below 42.88 nmol/L or nitrotyrosine = 1 if levels are above 42.88 nmol/L.