Figure 10.

Effect of the combined treatment on survival and body weight change in aged septic rats. Rats were subjected to CLP with injection of vehicle (normal saline) or GG-2 (80 nmol/kg of ghrelin and 50 μg/kg of GH) at 5 h after CLP. (A) Rats were monitored daily for 10 d. The survival rate was analyzed by Kaplan-Meier survival analysis and compared by the log-rank test (n = 14 per group). *P < 0.05 versus vehicle. (B) The daily body weight change of the surviving rats in a 10-d survival study. The percentage of body weight change is calculated by the difference from d 0. Data are expressed as mean ± SE.