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. 2016 Aug 30;12(8):e1005841. doi: 10.1371/journal.ppat.1005841

Fig 3. DENV infection modifies the splicing landscape of host cells.

Fig 3

(A) Strategy to detect and quantify alternative splicing isoforms in mock infected or DENV infected cells is depicted on the left. Representative autoradiographs and quantification of the inclusion/exclusion ratio for two alternative exon cassette events are shown (duplicates, mean ± SD). (B) Fold-change of inclusion/exclusion ratios for DENV or mock infected cells. A battery of endogenous alternative exon-cassette events (duplicates, mean ± SD) in A549 and Huh7 cells is shown. (C) DENV-induced changes in the splicing pattern of IKKε and MxA mRNAs. Quantification of alternative splicing events is shown for each case.