Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 30;12(8):e1005841. doi: 10.1371/journal.ppat.1005841

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 De Maio et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Fig 6 — (A) Time course of standard in vitro reaction showing radiolabeled substrate, intermediates and products of the splicing reaction. (B) Purified recombinant NS5 inhibits mature mRNA accumulation. A native or heat denature preparation of NS5 was added to the splicing reaction as indicated on the top of the gel. On the right, a graph showing dose-dependent inhibition of the splicing reaction by NS5. (C) Quantification of pre-mRNA and mature mRNA as a function of time in the presence of native NS5 or heated NS5 at 1μM.