Table 2. Allele and genotype frequencies of the rs368234815 IFNL4 gene polymorphism in the study population.
| Total a | Chronic infection | Spontaneous clearance | P value b | |
|---|---|---|---|---|
| (n = 138) | (n = 104) | (n = 34) | ||
| Allele model | 0.039 | |||
| ΔG | 102 (37.0) | 84 (40.4) | 18 (26.5) | |
| TT | 174 (63.0) | 124 (59.6) | 50 (73.5) | |
| Genotype model | 0.002 | |||
| ΔG/ΔG | 17 (12.3) | 12 (11.5) | 5 (14.7) | |
| TT/ΔG | 68 (49.3) | 60 (57.7) | 8 (23.5) | |
| TT/TT | 53 (38.4) | 32 (30.8) | 21 (61.8) | |
| ΔG dominant model c | 0.001 | |||
| ΔG/ΔG + TT/ΔG | 85 (71.6) | 72 (69.2) | 13 (38.2) | |
| TT/TT | 53 (38.4) | 32 (30.8) | 21 (61.8) |
a
Data are number (%) of patients.
b
Chi-square test; P values refer to comparison between chronic infection and spontaneous clearance.
c
ΔG dominant model: OR = 3.63, 95% CI: 1.51-8.89.