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. 2016 Aug 1;129(15):2950–2961. doi: 10.1242/jcs.183772

Fig. 1.

Fig. 1.

Mechanical properties and ECM composition of Cdh11−/− and WT mouse tissues. (A) Ultimate tensile strength (UTS) and (B) Young's moduli of bladder, skin and aorta tissues reported as normalized to corresponding WT tissues (n=4). (C) Histological examination of collagen content in cross-sections of skin, aorta and bladder tissue from Cdh11−/− and WT mice by Masson's trichrome staining. Scale bars: 200 µm. (D) Collagen content as quantified by hydroxyl-proline assay in Cdh11−/− skin, aorta and bladder tissues and reported after normalization to WT (n=4). (E) Histological examination of elastin content in cross-sections of skin, aorta and bladder tissue from Cdh11−/− and WT mice by Verhoeff's elastin staining. Scale bars: 200 µm. (F) Elastin content as quantified by ninhydrin assay in Cdh11−/− skin, aorta and bladder tissues and reported as after normalization to WT (n=4). All quantitative results are mean±s.d. *P<0.05 as compared to WT (unpaired two-tailed Student's t-test).